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Milk drug residue incidence drops for fifth straight year

Progressive Dairy Editor Dave Natzke Published on 05 January 2022
milk residue graphic

The FDA’s annual analysis shows dairy consumers are safer than ever when it comes to milk, with the industry setting record lows for samples testing positive for animal drug residues in the past year.

During fiscal year 2021 (Oct. 1, 2020, to Sept. 30, 2021), nearly 3.9 million milk samples were tested for animal drug residues. Of those, just 451 tested positive, according to FDA’s National Milk Drug Residue Database Fiscal Year 2021 report.

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The Grade “A” Pasteurized Milk Ordinance (PMO), which govern the state regulatory agencies in the implementation and enforcement of their Grade A milk safety program, requires that all bulk milk tankers be sampled and analyzed for animal drug residues before the milk is processed. Any bulk milk tanker found positive is rejected for human consumption.

The number of samples testing positive for drug residues in fiscal year 2021 was down from the year before and the lowest number of milk samples that tested positive for a drug residue in the 26 years data is available, back to 1994. By fiscal year, the number of milk samples testing positive for drug residues over the past decade was:

  • 2021 – 451
  • 2020 – 536
  • 2019 – 556
  • 2018 – 584
  • 2017 – 605
  • 2016 – 618
  • 2015 – 579
  • 2014 – 703
  • 2013 – 731
  • 2012 – 828

State and local agencies conduct drug residue tests at four “locations”:

  • Bulk milk pickup tankers (bulk raw milk from a dairy farm): Samples are taken on receipt of every tanker load at a milk receiving facility. Of more than 3.49 million samples, 290 (0.008%, or 8 thousandths of 1%) tested positive, resulting in the disposal of 13.1 million pounds of milk.

  • Producer (raw milk obtained from the bulk tank/silo from a dairy farm): Of 326,206 total samples, 160 (0.049%) tested positive, resulting in the disposal of 168,000 pounds of milk.

  • Other (milk from milk plant tank/silos, milk transport tankers, etc.): Of 43,159 total samples, none tested positive.

  • Samples of pasteurized fluid milk and milk products (finished dairy products in bulk or package form, after pasteurization, including milk, cream, condensed and dry milk and milk products, and condensed and dry whey and whey products) were tested. Of 31,009 total samples, one tested positive for animal drug residues.

Overall, about 13.24 million pounds of milk were found positive for a drug residue and disposed of in fiscal year 2021, down from fiscal year 2020’s total of 15.87 million pounds.

Testing for specific drugs

In addition to testing for presence of any drug residues, specific tests seek to identify residues from four different groups or individual drugs, using 23 different testing methods. Since some samples are tested for more than one drug residue, more than 4.04 million total tests were conducted, with 455 testing positive.

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Of samples testing positive, 451 samples were positive for beta lactams and four were positive for sulfonamides; none were positive for tetracyclines or aminoglycosides.

Of the 451 samples positive for beta lactams, 288 were drawn from bulk milk pickup tankers (both Grade A and non-Grade A), 162 were in samples drawn from bulk tanks/silos from dairy farms, and one was from a non-Grade A pasteurized product test.

Mandatory drug residue reporting is required by state regulatory agencies under the National Conference on Interstate Milk Shipments (NCIMS). NCIMS is a voluntary organization directed and controlled by member states to promote the availability of a high-quality milk supply.

The FDA and the NCIMS, through their collaborative efforts, have developed a cooperative, federal-state program (the Grade “A” Interstate Milk Shippers Program) to ensure the sanitary quality of Grade A milk and milk products shipped in interstate commerce.

The National Milk Drug Residue Data Base (NMDRD) is a voluntary industry reporting program, under contract to the FDA. Data reported to the NMDRD are for educational and analytical purposes, and are not intended or suitable for regulatory action or follow up.

The system includes all milk, Grade A and non-Grade A, commonly known as manufacturing grade. Grade A milk represents approximately 99% of the milk supply in the U.S. and is regulated through the NCIMS by the state regulatory agencies.  end mark

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ILLUSTRATION: Illustration by Sarah Johnston.

Dave Natzke
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